Nozdrenko, Dmytro; Prylutska, Svitlana; Bogutska, Kateryna; Nurishchenko, Natalia Y.; Abramchuk, Olga; Motuziuk, Olexandr; Prylutskyy, Yuriy; Scharff, Peter; Ritter, Uwe:
Effect of C₆₀ fullerene on recovery of muscle soleus in rats after atrophy induced by achillotenotomy
In: Life : open access journal, Jg. 12 (2022), Heft 3, 13 Seiten, Artikel 332
2022Artikel/Aufsatz in ZeitschriftOA Gold
Technische Universität Ilmenau (1992-) » Fakultät für Mathematik und Naturwissenschaften (1992-) » Institut für Chemie und Biotechnik (2011-) » Fachgebiet Chemie (2011-)
Damit verbunden: 1 Publikation(en)
Titel in Englisch:
Effect of C₆₀ fullerene on recovery of muscle soleus in rats after atrophy induced by achillotenotomy
Titel in Englisch (alternativ):
Effect of C60 fullerene on recovery of muscle soleus in rats after atrophy induced by achillotenotomy
Autor*in:
Nozdrenko, Dmytro
SCOPUS
15721188800
;Prylutska, Svitlana
SCOPUS
6507378333
;Bogutska, Kateryna
SCOPUS
6508280231
ORCID
0000-0003-0202-8042ORCID iD
;Nurishchenko, Natalia Y.
SCOPUS
6506511970
;Abramchuk, Olga
SCOPUS
57021803000
;Motuziuk, Olexandr
SCOPUS
56193664900
;Prylutskyy, Yuriy
SCOPUS
35585493200
Sonstiges
korrespondierende*r Autor*in
;Scharff, PeterTU
GND
130286222
ORCID
0000-0001-5615-0751ORCID iD
ORCID
0009-0002-4975-5386ORCID iD
SCOPUS
7004237276
Sonstiges
der Hochschule zugeordnet
;Ritter, UweTU
GND
137638221
ORCID
0000-0002-9315-4863ORCID iD
ResearcherID
F-8620-2014
SCOPUS
35269855400
SCOPUS
58076374700
Sonstiges
der Hochschule zugeordnet
korrespondierende*r Autor*in
Erscheinungsjahr:
2022
Open-Access-Publikationsweg:
OA Gold
DBT-ID
dbt_mods_00051817
DOI
10.3390/life12030332
PubMed ID
35330083
Scopus ID
85125473079
PPN:
1793815968
Sprache des Textes:
Englisch
Erschienen in
Life : open access journal
Erscheinungsort:
Basel
Verlag:
MDPI
Erscheinungsjahr:
2011
Open-Access-Publikationsweg:
OA Gold
in:
Jg. 12 (2022), Heft 3, 13 Seiten, Artikel 332
ISSN
2075-1729 Verfügbarkeit online & gedruckt anzeigen
PPN:
718627156
ZDB ID
2662250-6
URL:
https://ezb.ur.de/?2662250-6
Datenträgertyp:
Online-Ressource
Ressourcentyp:
Text
Access Rights:
Open Access
Peer Reviewed:
Ja
Teil der Statistik:
Nein
Schlagwort, Thema:
Achillotenotomy ; Atrophy ; Biomechanical and biochemical parameters of skeletal muscle contraction ; C60 fullerene ; Muscle soleus of rat
Datenträgertyp:
Online-Ressource
Ressourcentyp:
Text
Lizenztyp:
CC BY 4.0
Access Rights:
Open Access
Peer Reviewed:
Ja
Teil der Statistik:
Ja
DESTATIS Fachsystematik:
3730 Physikalische Chemie

Abstract in Englisch:

Biomechanical and biochemical changes in the muscle soleus of rats during imitation of hind limbs unuse were studied in the model of the Achilles tendon rupture (Achillotenotomy). Oral administration of water-soluble C60 fullerene at a dose of 1 mg/kg was used as a therapeutic agent throughout the experiment. Changes in the force of contraction and the integrated power of the muscle, the time to reach the maximum force response, the mechanics of fatigue processes development, in particular, the transition from dentate to smooth tetanus, as well as the levels of pro- and antioxidant balance in the blood of rats on days 15, 30 and 45 after injury were described. The obtained results indicate a promising prospect for C60 fullerene use as a powerful antioxidant for reducing and correcting pathological conditions of the muscular system arising from skeletal muscle atrophy.